Article: Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Gogliotti RG; Quinlan KA; Barlow CB; Heier CR; Heckman CJ; Didonato CJ J. Neurosci., 2012
Group ID | Genotype | Avg. gems per cell | MNs counted | MNs with gems | % MNs with gems | Number of cells with | N | |||
---|---|---|---|---|---|---|---|---|---|---|
0 Gems | 1 Gem | 2 Gems | 3 Gems | |||||||
Control | SMN2+/−, Smn2B-Neo/+ | 1.07 ± 0.19 | 155 | 106 | 68 ± 5% | 49 | 61 | 29 | 16 | 3 |
SMA | SMN2+/−, Smn2B-Neo/2B-Neo | 0.19 ± 0.02** | 149 | 26 | 17 ± 3% | 123 | 24 | 2 | 0 | 3 |
Motor Neuron Rescue SMA | SMN2+/−, Smn2B-Neo/2B-Neo, Hb9-Cre+/− | 0.63 ± 0.11† | 250 | 122 | 51 ± 2% | 128 | 99 | 13 | 10 | 5 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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